All posts by P. D. Mangan

The End of Cancer?

Cancer is the second leading cause of death in the U.S., and is one of the most dreaded diseases anywhere. It typically strikes older people more; some 90% of cancer is diagnosed in people over the age

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Is Alcohol an Anti-Aging Drug?

The consumption of alcohol has been shown, over and over again, to be associated with substantially lower death rates, especially from heart disease. Since aging is the biggest risk factor for the main

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Fasting Cleans the Brain

Intermittent fasting, or going without food for some period of time, has many benefits. Fasting lowers the level of the hormone insulin, which then allows fat-burning to take place. Weight loss is one

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Video: Geroprotectors

If you prefer the talking head version of my recent article on geroprotectors, here ya go.

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Geroprotectors: Anti-Aging Molecules

Geroprotectors are molecules that have been shown to slow aging and/or extend lifespan in experimental animals. A group of mainly Russian scientists have collaborated on a website that lists all known

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High-Fat Diet Doesn’t Cause Obesity

I wrote the other day about the less-than-optimal control animals and humans used in fasting and calorie-restriction studies. Partly this is due to the bad food that most people eat, as well as the substandard

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My Latest Video: Fasting, Calorie Restriction, and Aging

I recorded this video a few days ago, but thought I’d post it here for those of you who haven’t seen it yet. I discuss the implications of my recent post on anti-aging studies and the use of

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High-Intensity Interval Training Makes Fitness Fast

Ever since Dr. Kenneth Cooper introduced the concept of aerobics, we’ve been conditioned to believe that steady-state exercise at a moderate pace is the best, perhaps only, way to increase cardiorespiratory

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Anti-Aging Studies Are Seriously Compromised

Valter Longo, the noted scientist in aging research, has published a number of studies about fasting as an anti-aging measure. He’s developed a fasting-mimicking diet to be used for extended fasts,

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Five Ways to Fight Depression

Depression is a physical sickness that manifests as a mental illness. We know this because of the physical signs and symptoms that accompany depression: fatigue, insomnia or hypersomnia, significant weight

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Is Grass-Fed Beef Worth the Money?

In the recent post about best and worst protein supplements, a reader asked me whether I thought grass-fed whey was worth the money, and I answered in the negative. There’s a larger question: is

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Big Animals Die Younger

A recurring theme in research on aging is that of growth vs longevity. In essence, they’re opposed: more growth means shorter life, and less growth means longer life. The activation of physiological

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Best and Worst Protein Supplements

As part of some research I’m doing for another project, I looked into protein supplements. For myself, I’ve always confined my choice of protein supplement to the best ones, and haven’t

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Coffee, Whiskey, and Cigars Longevity Diet

It’s common for people who have lived a long time to divulge their “longevity secrets”, but in most cases they nor anyone else really knows what the answers to their long lives are. In

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Hormesis for Health and Longevity: A Guide

It’s obvious that people we refer to as couch potatoes have worse health than others, although these days the couch potatoes outnumber the others. The reason for their worse health is that they are

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Blood Donations, Blood Transfusions, and Iron

In the course of my book Dumping Iron, I discussed blood donations and some of their technicalities, specifically how they lower body iron stores.  In this short article I’ll discuss a few more

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