Category Archives for Aging

New Young Blood Study Implicates Iron in Aging

Executive Summary Surgically joining the circulatory systems of a young and an old mouse may rejuvenate the old mouse A new study finds that benefit to the older mouse are much smaller than harm to the

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Targeting Hypercoagulation for Anti-Aging

Coagulation (clotting) of the blood is an important process that keeps us from bleeding by stopping blood flow in a timely fashion. It’s intricately regulated by dozens of proteins, with positive

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Self-Stereotypes and How to Overcome Them

Stereotypes are empirical generalizations, and they are largely true. That’s how they got to be stereotypes. As such, they can be useful guides when dealing with other people, even other things.

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How Iron and Bacteria Combine to Promote Aging

Microbes in normally sterile body sites One of the more remarkable developments in recent years in the field of health and aging is the recognition that bacteria and other microbes such as fungi can be

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The Garbage Catastrophe of Aging and How to Avoid It

Aging just is damage accumulation Aging is the accumulation of damage and nothing more. As the level of damage rises, cells and the tissue made from them function poorly, and this in turn causes increased

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Cracking the Aging Code: The Science Book of the Year

In his new book, Cracking the Aging Code: The New Science of Growing Old and What It Means for Staying Young, Josh Mitteldorf, who has studied aging for decades and writes about it at his website, explores

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The 80/20 Rule in Fighting Aging and Obesity

Vilfredo Pareto first formulated the rule named after him, the Pareto Principle, or as it’s now often known, the 80/20 Rule. The rule states that in many phenomena, 20% of the inputs generate 80%

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Do Microbes Cause Aging?

Microscopic organisms — bacteria, fungi, protozoa, and viruses — are extremely abundant on the planet; the estimated number of bacteria alone is ~5 x 10^30, and their total content of carbon,

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Weightlifting Is Anti-Aging

In my book Muscle Up, I gave a host of reasons why strength training — which most people accomplish through lifting weights — is a uniquely healthful exercise and much better than aerobic or

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How I Plan to Reach 110 Years of Age

It’s strange. At 61 years old, according to statistics and common knowledge, I’m supposed to be getting to the point where age-related diseases start to get me. Aside from the usual, dreaded

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Ten Questions and Answers with Dr. Michael Fossel

Michael Fossel, M.D., PhD, is the author of The Telomerase Revolution, The Immortality Edge, and Cells, Aging, and Human Disease. He is the president and co-founder of Telocyte, a company that aims to

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Iron Shortens Telomeres and Damages DNA

I’ve been reading the new book by Michael Fossel, The Telomerase Revolution: The Enzyme That Holds the Key to Human Aging …and Will Soon Lead to Longer, Healthier Lives. I think anyone who finds

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How to Make Cheap Anti-Aging Supplements

There are a number of supplements that are marketed as having anti-aging activity, and that are expensive. The two that are best-known to me are Protandim and Longevinex. But let’s see how to make

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Iron Chelators More Effective Than Rapamycin for Life Extension

The scientist Mikhail Blagosklonny is best-known for his advocacy of the “quasi-program” theory of aging. What this means is that aging is the continuation of the development program; certain

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The Most Potent Life Extension Substance Ever

Plant extracts more potent than metformin and rapamycin Recently, a research group screened a number (37 to be exact) of plant extracts to see what effect they might have on slowing aging and extending

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Deadlift, 305

I posted this very short video on Twitter the other day, but here it is for those who may have missed it. See? I really do this stuff. My form wasn’t great; I didn’t keep my back straight among

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Only Ten Percent Dietary Restriction Significantly Extends Lifespan

Calorie (or dietary) restriction is the most effective intervention for increasing lifespan in laboratory animals. It activates or deactivates a number of physiological pathways, leading to increased stress

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Why do older men have lower blood volume?

You learn something new every day, or anyway I try to. In the course of researching something else I discovered a study that showed that older men have substantially lower blood volume than younger men.(1)

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