Category Archives for Mitochondria

How to Make Lifting Weights a Maximum Anti-Aging Workout

A recent study found that high-intensity interval training (HIIT) robustly increased both aerobic capacity and mitochondrial function in both old and young people. The older people saw a greater increase

READ MORE

Control Your Mitochondria or They Will Control You

Mitochondria are small organelles within cells, popularly known as the powerhouses of the cell, since their main function is to burn energy. With a few exceptions, such as red blood cells, every cell in

READ MORE

Chocolate is an exercise mimetic

(–)-Epicatechin enhances fatigue resistance and oxidative capacity in mouse muscle Abstract  The flavanol (–)-epicatechin, a component of cacao (cocoa), has been shown to have multiple health benefits

READ MORE

Testosterone, fatigue, energy

One of the symptoms of low testosterone (T), also known as hypogonadism, is fatigue or low energy levels. A couple of papers give some insight into how this works, as well as the extent to which replacing

READ MORE

Increasing longevity through mitochondrial signaling

The NAD+/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling Authors Laurent Mouchiroud, Riekelt H. Houtkooper, Norman Moullan, Elena Katsyuba, Dongryeol Ryu,

READ MORE

Chocolate improves mitochondrial function and increases mitochondrial biogenesis

Alterations in skeletal muscle indicators of mitochondrial structure and biogenesis in patients with type 2 diabetes and heart failure: effects of epicatechin rich cocoa. (-)-Epicatechin (Epi), a flavanol

READ MORE

Mitochondrial Theory of Aging: Importance to Explain Why Females Live Longer Than Males

Mitochondrial Theory of Aging: Importance to Explain Why Females Live Longer Than Males Females live longer than males in many species, including humans. This can be explained on the basis of the mitochondrial

READ MORE

Rapamycin does not compromise muscle endurance

The following study partly answers something I’ve long wondered about, whether the anti-aging drug rapamycin can compromise muscle endurance or performance: Rapamycin doses sufficient to extend lifespan

READ MORE

Glucose restriction and life extension

Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress. Schulz TJ, Zarse K, Voigt A, Urban N, Birringer M, Ristow M.SourceDepartment

READ MORE

New paper by Ristow group on mitochondrial hormesis

Mitochondrial hormesis links low-dose arsenite exposure to lifespan extension. Schmeisser S, Schmeisser K, Weimer S, Groth M, Priebe S, Fazius E, Kuhlow D, Pick D, Einax JW, Guthke R, Platzer M, Zarse

READ MORE

Nutraceutical with leucine and B6 causes fat-burning

Effects of a leucine and pyridoxine-containing nutraceutical on fat oxidation, and oxidative and inflammatory stress in overweight and obese subjects. Abstract Leucine stimulates tissue protein synthesis

READ MORE

Methylene blue enhances memory

Methylene blue is a common and cheap dye used in biology and medicine. Neurometabolic mechanisms for memory enhancement and neuroprotection of methylene blue. Rojas JC, Bruchey AK, Gonzalez-Lima F.Source Departments

READ MORE

Mitochondrial dysfunction in chronic fatigue

Mitochondrial dysfunction and the pathophysiology of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Abstract The objectives of this study are to test the hypothesis that the fatigue and accompanying

READ MORE