Leave a Comment: Name * E-Mail * Website Comment Notify me of follow-up comments by email. 5 comments Joshua says December 30, 2015 Is there any chance you might be able to provide transcriptions of these podcasts? Some other sites (Art of Manliness, Chris Kresser) do this, and I find it very helpful. I can read material much, much more quickly than I can listen to it. In fact, I really don’t ever listen to podcasts. I’d imagine trying to manually transcribe them would be far too time-consuming, but perhaps there are some speech-to-text programs that you could run to generate transcriptions? Anyways, the blog has continued to improve since I first discovered it. Nice work! Reply Name* Email* Website Comment Cancel P. D. Mangan says December 30, 2015 Thanks, Joshua. One of the programs I use may be able to transcribe, I’ll have a look. Reply Name* Email* Website Comment Cancel Zacharias says January 11, 2016 Around the 21 minute mark you state that most of the effects of calorie restriction seem due to the fact that animals that are calorie restricted eat less protein. I do intermittent fasting because of autophagy. But I also use a low carb diet, a little bit paleo-ish. So does it make sense to combine paleo or a low carb diet with intermittent fasting? Or are the effects of IF lost then? Another question: Does Glycine break the fast? I don’t eat before noon but I drink black coffee in the morning, and recently I started to drink a mixture of: Hot water with cacao powder, ginseng powder, macca powder, magnesium/calcium powder. I want to add Glycine powder to the mix. Anyway, great site, great podcast. One note though: I couldn’t find the podcast via search on your site, needed to use Google, not sure if that’s just me. Maybe you should make the podcast more visible on your site. Reply Name* Email* Website Comment Cancel P. D. Mangan says January 11, 2016 Thanks, Zacharias. I myself eat a low-carb paleo style diet and practice intermittent fasting. I’m grappling with the fact that lower protein intake seems to be a main element of the mechanism of calorie restriction. One thing I’ve done is protein cycling: http://roguehealthandfitness.com/protein-cycling-diet-for-life-extension/ The effects of IF are not lost with the paleo/IF combo. As for glycine, I would be careful about adding amino acids during fasting. BCAAs will definitely stop autophagy, glycine may not, but caution is ion order. Amino acids are important nutrients that activate mTOR, the growth machinery. BTW, as to finding the podcast, if you look on lower right side of the site, there’s a list of categories, of which “podcast” is one. Of course I want people to be able to find what they need, and I don’t know how you searched, and I appreciate your alerting me to it. Reply Name* Email* Website Comment Cancel Zacharias says January 18, 2016 @podcast, lower right side of the site Yeah found it, thanks, I still think it should be more prominent, because it’s good! I will listen regularly. @protein cycling Thanks, great article! I will definitely add this to my things-to-experiment-with-list. @glycine in the morning Is there a way to find out if autophagy has been stopped other than bloodwork? And I guess all the other ingredients (powder) I drink in the morning are okay then. Reply Name* Email* Website Comment Cancel Add Your Reply Name * E-Mail * Website Comment Notify me of follow-up comments by email.